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Magnitude and sign epistasis among deleterious mutations in a positive-sense plant RNA virus

How epistatic interactions between mutations determine the genetic architecture of fitness is of central importance in evolution. The study of epistasis is particularly interesting for RNA viruses because of their genomic compactness, lack of genetic redundancy, and apparent low complexity. Moreover...

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Autori principali: Lalić, J, Elena, S F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400743/
https://ncbi.nlm.nih.gov/pubmed/22491062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hdy.2012.15
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