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Magnitude and sign epistasis among deleterious mutations in a positive-sense plant RNA virus

How epistatic interactions between mutations determine the genetic architecture of fitness is of central importance in evolution. The study of epistasis is particularly interesting for RNA viruses because of their genomic compactness, lack of genetic redundancy, and apparent low complexity. Moreover...

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Bibliografiske detaljer
Main Authors: Lalić, J, Elena, S F
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400743/
https://ncbi.nlm.nih.gov/pubmed/22491062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hdy.2012.15
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