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Magnitude and sign epistasis among deleterious mutations in a positive-sense plant RNA virus

How epistatic interactions between mutations determine the genetic architecture of fitness is of central importance in evolution. The study of epistasis is particularly interesting for RNA viruses because of their genomic compactness, lack of genetic redundancy, and apparent low complexity. Moreover...

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Detalhes bibliográficos
Main Authors: Lalić, J, Elena, S F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400743/
https://ncbi.nlm.nih.gov/pubmed/22491062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hdy.2012.15
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