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Inhibition of Tumor Angiogenesis and Growth by Nanoparticle-Mediated p53 Gene Therapy in Mice

Mutation of the p53 tumor suppressor gene, the most common genetic alteration in human cancers, results in more aggressive disease and increased resistance to conventional therapies. Aggressiveness may be related to the increased angiogenic activity of cancer cells containing mutant p53. To restore...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Prabha, Swayam, Sharma, Blanka, Labhasetwar, Vinod
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400709/
https://ncbi.nlm.nih.gov/pubmed/22595792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2012.26
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