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Nanoparticle-mediated p53 gene therapy for tumor inhibition
The p53 tumor suppressor gene is mutated in 50% of human cancers, resulting in more aggressive disease with greater resistance to chemotherapy and radiation therapy. Advances in gene therapy technologies offer a promising approach to restoring p53 function. We have developed polymeric nanoparticles...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3339849/ https://ncbi.nlm.nih.gov/pubmed/22553503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-010-0008-9 |
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