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Comprehensive Identification and Annotation of Cell Type-Specific and Ubiquitous CTCF-Binding Sites in the Human Genome

Chromatin insulators are DNA elements that regulate the level of gene expression either by preventing gene silencing through the maintenance of heterochromatin boundaries or by preventing gene activation by blocking interactions between enhancers and promoters. CCCTC-binding factor (CTCF), a ubiquit...

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Detalhes bibliográficos
Main Authors: Chen, Hebing, Tian, Yao, Shu, Wenjie, Bo, Xiaochen, Wang, Shengqi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400636/
https://ncbi.nlm.nih.gov/pubmed/22829947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041374
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