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Adaptive Evolution and the Birth of CTCF Binding Sites in the Drosophila Genome

Changes in the physical interaction between cis-regulatory DNA sequences and proteins drive the evolution of gene expression. However, it has proven difficult to accurately quantify evolutionary rates of such binding change or to estimate the relative effects of selection and drift in shaping the bi...

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Detalhes bibliográficos
Main Authors: Ni, Xiaochun, Zhang, Yong E., Nègre, Nicolas, Chen, Sidi, Long, Manyuan, White, Kevin P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491045/
https://ncbi.nlm.nih.gov/pubmed/23139640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001420
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