Overexpression of TGF-ß1 in Macrophages Reduces and Stabilizes Atherosclerotic Plaques in ApoE-Deficient Mice

Although macrophages represent the hallmark of both human and murine atherosclerotic lesions and have been shown to express TGF-ß1 (transforming growth factor β1) and its receptors, it has so far not been experimentally addressed whether the pleiotropic cytokine TGF-ß1 may influence atherogenesis by...

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Detalhes bibliográficos
Main Authors: Reifenberg, Kurt, Cheng, Fei, Orning, Carolin, Crain, Jeanine, Küpper, Ines, Wiese, Elena, Protschka, Martina, Blessing, Manfred, Lackner, Karl J., Torzewski, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400574/
https://ncbi.nlm.nih.gov/pubmed/22829904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040990
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