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Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data
Mammalian RNA complexity is regulated through interactions of RNA-binding proteins (RBPs) with their target transcripts. High-throughput sequencing together with UV-crosslinking and immunoprecipitation (HITS-CLIP) is able to globally map RBP-binding footprint regions at the resolution of ~30–60 nucl...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3400429/ https://ncbi.nlm.nih.gov/pubmed/21633356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1873 |
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