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p47(phox)-deficient immune microenvironment signals dysregulate naive T cell apoptosis
The phagocyte NADPH oxidase is a multi-component enzyme complex mediating microbial killing. We find that NADPH oxidase p47(phox) deficient (p47(phox-/-)) chronic granulomatous disease (CGD) mice develop lymph node hyperplasia even without obvious infection, where increased number of T and B lymphoc...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3400273/ https://ncbi.nlm.nih.gov/pubmed/18806761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2008.129 |
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