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Distinct IFNG Methylation in a Subset of Ulcerative Colitis Patients Based upon Reactivity to Microbial Antigens

BACKGROUND: High antibody reactivity toward microbial antigens in Crohn’s disease patients is predictive of a more aggressive disease course. However, few ulcerative colitis patients exhibit serologic reactivity towards microbial antigens. Mucosal expression of IFN-γ plays a pivotal role in IBD path...

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Autori principali: Gonsky, Rivkah, Deem, Richard L, Landers, Carol J, Derkowski, Carrie A, Berel, Dror, McGovern, Dermot P B, Targan, Stephan R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400263/
https://ncbi.nlm.nih.gov/pubmed/20848535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21352
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