Genetic Evidence that Thyroid Hormone is Indispensable for Prepubertal IGF-I Expression and Bone Acquisition in Mice

Understanding how bone growth is regulated by hormonal and mechanical factors during early growth periods is important for optimizing the attainment of peak bone mass to prevent or postpone the occurance of fragility fractures later in life. Using genetic mouse models that are deficient in thyroid h...

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Autors principals: Xing, Weirong, Govoni, Kristen, Donahue, Leah Rae, Kesavan, Chandrasekhar, Wergedal, Jon, Long, Carlin, Bassett, J.H. Duncan, Gogakos, Apostolos, Wojcicka, Anna, Williams, Graham R., Mohan, Subburaman
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399953/
https://ncbi.nlm.nih.gov/pubmed/22513648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1551
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