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BAY61-3606 Affects the Viability of Colon Cancer Cells in a Genotype-Directed Manner
BACKGROUND: K-RAS mutation poses a particularly difficult problem for cancer therapy. Activating mutations in K-RAS are common in cancers of the lung, pancreas, and colon and are associated with poor response to therapy. As such, targeted therapies that abrogate K-RAS-induced oncogenicity would be o...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3399817/ https://ncbi.nlm.nih.gov/pubmed/22815993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041343 |
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