A Review of VEGF/VEGFR-Targeted Therapeutics for Recurrent Glioblastoma

Glioblastoma, the most common primary malignant brain tumor among adults, is a highly angiogenic and deadly tumor. Angiogenesis in glioblastoma, driven by hypoxia-dependent and independent mechanisms, is primarily mediated by vascular endothelial growth factor (VEGF), and generates blood vessels wit...

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Detalhes bibliográficos
Main Authors: Reardon, David A., Turner, Scott, Peters, Katherine B., Desjardins, Annick, Gururangan, Sridharan, Sampson, John H., McLendon, Roger E., Herndon, James E., Jones, Lee W., Kirkpatrick, John P., Friedman, Allan H., Vredenburgh, James J., Bigner, Darell D., Friedman, Henry S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399727/
https://ncbi.nlm.nih.gov/pubmed/21464146
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