A Review of VEGF/VEGFR-Targeted Therapeutics for Recurrent Glioblastoma

Glioblastoma, the most common primary malignant brain tumor among adults, is a highly angiogenic and deadly tumor. Angiogenesis in glioblastoma, driven by hypoxia-dependent and independent mechanisms, is primarily mediated by vascular endothelial growth factor (VEGF), and generates blood vessels wit...

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Bibliografiske detaljer
Main Authors: Reardon, David A., Turner, Scott, Peters, Katherine B., Desjardins, Annick, Gururangan, Sridharan, Sampson, John H., McLendon, Roger E., Herndon, James E., Jones, Lee W., Kirkpatrick, John P., Friedman, Allan H., Vredenburgh, James J., Bigner, Darell D., Friedman, Henry S.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399727/
https://ncbi.nlm.nih.gov/pubmed/21464146
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