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Metabolic Toxicity Screening Using Electrochemiluminescence Arrays Coupled with Enzyme-DNA Biocolloid Reactors and Liquid Chromatography–Mass Spectrometry

New chemicals or drugs must be guaranteed safe before they can be marketed. Despite widespread use of bioassay panels for toxicity prediction, products that are toxic to a subset of the population often are not identified until clinical trials. This article reviews new array methodologies based on e...

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Main Authors: Hvastkovs, Eli G., Schenkman, John B., Rusling, James F.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399491/
https://ncbi.nlm.nih.gov/pubmed/22482786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.anchem.111808.073659
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