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Normal Mode Gating Motions of a Ligand-Gated Ion Channel Persist in a Fully Hydrated Lipid Bilayer Model

[Image: see text] We have previously used molecular modeling and normal-mode analyses combined with experimental data to visualize a plausible model of a transmembrane ligand-gated ion channel. We also postulated how the gating motion of the channel may be affected by the presence of various ligands...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bertaccini, Edward J., Trudell, James R., Lindahl, Erik
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2010
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399477/
https://ncbi.nlm.nih.gov/pubmed/22816018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn100026t
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