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18α-Glycyrrhetinic Acid Down-Regulates Expression of Type I and III Collagen via TGF-Β1/Smad Signaling Pathway in Human and Rat Hepatic Stellate Cells

Objective: To investigate the effects of 18α-glycyrrhetinic acid (18α-GA) on the expression of type I and III collagen in human and rat hepatic stellate cells (HSC) and to explore the role of TGF-β1/Smad signaling pathway involved. Methods: Following 18α-GA treatment, the cell viability and cell gro...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zong, Lei, Qu, Ying, Xu, Ming-yi, Dong, Yu-wei, Lu, Lun-gen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Ivyspring International Publisher 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399217/
https://ncbi.nlm.nih.gov/pubmed/22811611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.4395
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