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Early Response of α2(I) Collagen to Acetaldehyde in Human Hepatic Stellate Cells is TGF-β Independent

Acetaldehyde is fibrogenic and induces the expression of type I collagen genes in hepatic stellate cells. Some of these acetaldehyde-dependent events are mediated by H(2)O(2) and thus establish a direct connection between oxidative stress and collagen upregulation. We localized to the −378 to −183 r...

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Main Authors: Svegliati-Baroni, Gianluca, Inagaki, Yutaka, Rincon-Sanchez, Ana-Rosa, Else, Cindy, Saccomanno, Stefania, Benedetti, Antonio, Ramirez, Francesco, Rojkind, Marcos
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1314984/
https://ncbi.nlm.nih.gov/pubmed/16025520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.20798
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