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SLAT/Def6 plays a critical role in the pathogenic process of experimental autoimmune uveitis (EAU)

PURPOSE: SWAP 70-like adaptor of T cells (SLAT; aka Def6) is a recently discovered guanine nucleotide exchange factor for Rho guanosine triphosphate (GTP)ases that has been previously shown to play a role in cluster of differentiation(CD)4+ T cell activation, T-helper (Th)1/Th2/Th17 differentiation...

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Autors principals: Vistica, Barbara P., Shi, Guangpu, Nugent, Lindsey, Tan, Cuiyan, Altman, Amnon, Gery, Igal
Format: Artigo
Idioma:Inglês
Publicat: Molecular Vision 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398495/
https://ncbi.nlm.nih.gov/pubmed/22815639
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