Novel late-onset Alzheimer disease loci variants associate with brain gene expression

OBJECTIVE: Recent genome-wide association studies (GWAS) of late-onset Alzheimer disease (LOAD) identified 9 novel risk loci. Discovery of functional variants within genes at these loci is required to confirm their role in Alzheimer disease (AD). Single nucleotide polymorphisms that influence gene e...

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Main Authors: Allen, Mariet, Zou, Fanggeng, Chai, High Seng, Younkin, Curtis S., Crook, Julia, Pankratz, V. Shane, Carrasquillo, Minerva M., Rowley, Christopher N., Nair, Asha A., Middha, Sumit, Maharjan, Sooraj, Nguyen, Thuy, Ma, Li, Malphrus, Kimberly G., Palusak, Ryan, Lincoln, Sarah, Bisceglio, Gina, Georgescu, Constantin, Schultz, Debra, Rakhshan, Fariborz, Kolbert, Christopher P., Jen, Jin, Haines, Jonathan L., Mayeux, Richard, Pericak-Vance, Margaret A., Farrer, Lindsay A., Schellenberg, Gerard D., Petersen, Ronald C., Graff-Radford, Neill R., Dickson, Dennis W., Younkin, Steven G., Ertekin-Taner, Nilüfer
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398432/
https://ncbi.nlm.nih.gov/pubmed/22722634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182605801
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