Novel late-onset Alzheimer disease loci variants associate with brain gene expression

OBJECTIVE: Recent genome-wide association studies (GWAS) of late-onset Alzheimer disease (LOAD) identified 9 novel risk loci. Discovery of functional variants within genes at these loci is required to confirm their role in Alzheimer disease (AD). Single nucleotide polymorphisms that influence gene e...

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Hauptverfasser: Allen, Mariet, Zou, Fanggeng, Chai, High Seng, Younkin, Curtis S., Crook, Julia, Pankratz, V. Shane, Carrasquillo, Minerva M., Rowley, Christopher N., Nair, Asha A., Middha, Sumit, Maharjan, Sooraj, Nguyen, Thuy, Ma, Li, Malphrus, Kimberly G., Palusak, Ryan, Lincoln, Sarah, Bisceglio, Gina, Georgescu, Constantin, Schultz, Debra, Rakhshan, Fariborz, Kolbert, Christopher P., Jen, Jin, Haines, Jonathan L., Mayeux, Richard, Pericak-Vance, Margaret A., Farrer, Lindsay A., Schellenberg, Gerard D., Petersen, Ronald C., Graff-Radford, Neill R., Dickson, Dennis W., Younkin, Steven G., Ertekin-Taner, Nilüfer
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398432/
https://ncbi.nlm.nih.gov/pubmed/22722634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182605801
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