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Myeloid Suppressor Cell Depletion Augments Antitumor Activity in Lung Cancer
BACKGROUND: Myeloid derived suppressor cells (MDSC) are important regulators of immune responses. We evaluated the mechanistic role of MDSC depletion on antigen presenting cell (APC), NK, T cell activities and therapeutic vaccination responses in murine models of lung cancer. PRINCIPAL FINDINGS: Ind...
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Autors principals: | , , , , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Public Library of Science
2012
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3398024/ https://ncbi.nlm.nih.gov/pubmed/22815789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040677 |
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