Role of CXCR3 Ligands in IL-7/IL-7Rα-Fc mediated antitumor activity in Lung Cancer

PURPOSE: We evaluated the utility of chimeric γc homeostatic cytokine, IL-7/IL-7Rα-Fc, to restore host APC and T cell activities in lung cancer. EXPERIMENTAL DESIGN: Utilizing murine lung cancer models we determined the antitumor efficacy of IL-7/IL-7Rα-Fc. APC, T cell, cytokine analyses, neutraliza...

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Détails bibliographiques
Auteurs principaux: Andersson, Åsa, Srivastava, Minu K., Harris-White, Marni, Huang, Min, Zhu, Li, Elashoff, David, Strieter, Robert M., Dubinett, Steven M., Sharma, Sherven
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118413/
https://ncbi.nlm.nih.gov/pubmed/21636553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-3346
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