Physalin F Induces Cell Apoptosis in Human Renal Carcinoma Cells by Targeting NF-kappaB and Generating Reactive Oxygen Species

BACKGROUND: The aim of this study was to determine the molecular mechanisms of physalin F, an effective purified extract of Physalis angulata L. (Solanacae), in renal carcinoma A498 cells. METHODOLOGY/PRINCIPAL FINDINGS: Physalin F was observed to significantly induce cytotoxicity of three human ren...

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Detalhes bibliográficos
Main Authors: Wu, Szu-Ying, Leu, Yann-Lii, Chang, Ya-Ling, Wu, Tian-Shung, Kuo, Ping-Chung, Liao, Yu-Ren, Teng, Che-Ming, Pan, Shiow-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398016/
https://ncbi.nlm.nih.gov/pubmed/22815798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040727
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