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Excision of a viral reprogramming cassette by delivery of synthetic Cre mRNA

The generation of patient-specific induced pluripotent stem (iPS) cells provides an invaluable resource for cell therapy, in vitro modeling of human disease, and drug screening. To date, most human iPS cells have been generated with integrating retro- and lenti-viruses and are limited in their poten...

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Hlavní autoři: Loh, Yuin-Han, Yang, Jimmy Chen, De Los Angeles, Alejandro, Guo, Chunguang, Cherry, Anne, Rossi, Derrick J., Park, In-Hyun, Daley, George Q.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397830/
https://ncbi.nlm.nih.gov/pubmed/22605648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470151808.sc04a05s21
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