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Excision of a viral reprogramming cassette by delivery of synthetic Cre mRNA
The generation of patient-specific induced pluripotent stem (iPS) cells provides an invaluable resource for cell therapy, in vitro modeling of human disease, and drug screening. To date, most human iPS cells have been generated with integrating retro- and lenti-viruses and are limited in their poten...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397830/ https://ncbi.nlm.nih.gov/pubmed/22605648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470151808.sc04a05s21 |
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