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Differential Accumulation of Secreted APP Metabolites in Ocular Fluids
The Alzheimer amyloid-β (Aβ) accumulates in several types of retinal degeneration and in Alzheimer disease (AD), but its source has been unclear. We detected the neuronal 695 amino acid form of Aβ-precursor protein (AβPP) in the normal retina and AβPP751 in the retinal pigment epithelium (RPE) and a...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397687/ https://ncbi.nlm.nih.gov/pubmed/20413851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-100210 |
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