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Differential Accumulation of Secreted APP Metabolites in Ocular Fluids

The Alzheimer amyloid-β (Aβ) accumulates in several types of retinal degeneration and in Alzheimer disease (AD), but its source has been unclear. We detected the neuronal 695 amino acid form of Aβ-precursor protein (AβPP) in the normal retina and AβPP751 in the retinal pigment epithelium (RPE) and a...

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Detalhes bibliográficos
Main Authors: Prakasam, Annamalai, Muthuswamy, Anusuya, Ablonczy, Zsolt, Greig, Nigel H., Fauq, Abdul, Rao, Kosagisharaf Jagannatha, Pappolla, Miguel A., Sambamurti, Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397687/
https://ncbi.nlm.nih.gov/pubmed/20413851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-100210
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