Mycalamide A Shows Cytotoxic Properties and Prevents EGF-Induced Neoplastic Transformation through Inhibition of Nuclear Factors

Mycalamide A, a marine natural compound previously isolated from sponges, is known as a protein synthesis inhibitor with potent antitumor activity. However, the ability of this compound to prevent malignant transformation of cells has never been examined before. Here, for the first time, we report t...

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Bibliographic Details
Main Authors: Dyshlovoy, Sergey A., Fedorov, Sergey N., Kalinovsky, Anatoly I., Shubina, Larisa K., Bokemeyer, Carsten, Stonik, Valentin A., Honecker, Friedemann
Format: Artigo
Language:Inglês
Published: MDPI 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397435/
https://ncbi.nlm.nih.gov/pubmed/22822368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md10061212
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