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Mycalamide A Shows Cytotoxic Properties and Prevents EGF-Induced Neoplastic Transformation through Inhibition of Nuclear Factors

Mycalamide A, a marine natural compound previously isolated from sponges, is known as a protein synthesis inhibitor with potent antitumor activity. However, the ability of this compound to prevent malignant transformation of cells has never been examined before. Here, for the first time, we report t...

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Main Authors: Dyshlovoy, Sergey A., Fedorov, Sergey N., Kalinovsky, Anatoly I., Shubina, Larisa K., Bokemeyer, Carsten, Stonik, Valentin A., Honecker, Friedemann
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397435/
https://ncbi.nlm.nih.gov/pubmed/22822368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md10061212
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