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Simultaneous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC-MS/MS method: application to an oral bioavailability study of genistein in mice
The purpose of this research was to develop a sensitive and reproducible UPLC-MS/MS method to simultaneously quantify genistein, genistein-7-O-glucuronide (G-7-G), genistein-4’-O-glucuronide (G-4’-G), genistein-4’-O-sulfate (G-4’-S) and genistein-7-Osulfate (G-7-S) in mouse blood samples. After the...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397253/ https://ncbi.nlm.nih.gov/pubmed/20378296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2010.03.011 |
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