DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards.
Nitrogen mustards alkylate DNA primarily at the N7 position of guanine. Using an approach analogous to that of the Maxam-Gilbert procedure for DNA sequence analysis, we have examined the relative frequencies of alkylation for a number of nitrogen mustards at different guanine-N7 sites on a DNA fragm...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1986
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC339715/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3960738/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.7.2971 |
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