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DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards.

Nitrogen mustards alkylate DNA primarily at the N7 position of guanine. Using an approach analogous to that of the Maxam-Gilbert procedure for DNA sequence analysis, we have examined the relative frequencies of alkylation for a number of nitrogen mustards at different guanine-N7 sites on a DNA fragm...

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Bibliografische gegevens
Hoofdauteurs: Mattes, W B, Hartley, J A, Kohn, K W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1986
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC339715/
https://ncbi.nlm.nih.gov/pubmed/3960738
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