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Multi-ethnic Distribution of Clinically Relevant CYP2C Genotypes and Haplotypes
To determine CYP2C19 and CYP2C8 allele frequencies, 28 coding and/or functional variants were genotyped in 1250 African-American, Asian, Caucasian, Hispanic and Ashkenazi Jewish (AJ) individuals. The combined CYP2C19 variant allele frequencies ranged from ~0.30–0.41; however, the CYP2C8 frequencies...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396745/ https://ncbi.nlm.nih.gov/pubmed/22491019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2012.10 |
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