In vivo regulation of the heme oxygenase-1 gene in humanized transgenic mice

Heme oxygenase-1 (HO-1) catalyzes the rate-limiting step in heme degradation producing equimolar amounts of carbon monoxide, iron, and biliverdin. Induction of HO-1 is a beneficial response to tissue injury in diverse animal models of diseases including acute kidney injury. In vitro analysis has sho...

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Main Authors: Kim, Junghyun, Zarjou, Abolfazl, Traylor, Amie M., Bolisetty, Subhashini, Jaimes, Edgar A., Hull, Travis D., George, James F., Mikhail, Fady M., Agarwal, Anupam
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396739/
https://ncbi.nlm.nih.gov/pubmed/22495295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.102
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