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In vivo regulation of the heme oxygenase-1 gene in humanized transgenic mice
Heme oxygenase-1 (HO-1) catalyzes the rate-limiting step in heme degradation producing equimolar amounts of carbon monoxide, iron, and biliverdin. Induction of HO-1 is a beneficial response to tissue injury in diverse animal models of diseases including acute kidney injury. In vitro analysis has sho...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396739/ https://ncbi.nlm.nih.gov/pubmed/22495295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.102 |
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