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Physiologically aged red blood cells undergo erythrophagocytosis in vivo but not in vitro

BACKGROUND: The lifespan of red blood cells is terminated when macrophages remove senescent red blood cells by erythrophagocytosis. This puts macrophages at the center of systemic iron recycling in addition to their functions in tissue remodeling and innate immunity. Thus far, erythrophagocytosis ha...

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Autori principali: Gottlieb, Yehonatan, Topaz, Orit, Cohen, Lyora A., Yakov, Liat David, Haber, Tom, Morgenstern, Abigail, Weiss, Avital, Chait Berman, Karen, Fibach, Eitan, Meyron-Holtz, Esther G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396668/
https://ncbi.nlm.nih.gov/pubmed/22331264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.057620
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