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Increased erythrophagocytosis induces ferroptosis in red pulp macrophages in a mouse model of transfusion

Macrophages play important roles in recycling iron derived from the clearance of red blood cells (RBCs). They are also a critically important component of host defense, protecting against invading pathogens. However, the effects on macrophage biology of acutely ingesting large numbers of RBCs are no...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Youssef, Lyla A., Rebbaa, Abdelhadi, Pampou, Sergey, Weisberg, Stuart P., Stockwell, Brent R., Hod, Eldad A., Spitalnik, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992863/
https://ncbi.nlm.nih.gov/pubmed/29666112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-12-822619
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