PI3Kδ Is Essential for Tumor Clearance Mediated by Cytotoxic T Lymphocytes

BACKGROUND: PI3Kδ is a lipid kinase of the phosphoinositide 3-kinase class 1A family and involved in early signaling events of leukocytes regulating proliferation, differentiation and survival. Currently, several inhibitors of PI3Kδ are under investigation for the treatment of hematopoietic malignan...

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Main Authors: Putz, Eva Maria, Prchal-Murphy, Michaela, Simma, Olivia Annabella, Forster, Florian, Koenig, Xaver, Stockinger, Hannes, Piekorz, Roland P., Freissmuth, Michael, Müller, Mathias, Sexl, Veronika, Zebedin-Brandl, Eva
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396622/
https://ncbi.nlm.nih.gov/pubmed/22808277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040852
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