Iontophoresis of Endothelin Receptor Antagonists in Rats and Men

INTRODUCTION: The treatment of scleroderma-related digital ulcers is challenging. The oral endothelin receptor antagonist (ERA) bosentan has been approved but it may induce liver toxicity. The objective of this study was to test whether ERAs bosentan and sitaxentan could be locally delivered using i...

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Sonraí Bibleagrafaíochta
Main Authors: Roustit, Matthieu, Blaise, Sophie, Arnaud, Claire, Hellmann, Marcin, Millet, Claire, Godin-Ribuot, Diane, Dufournet, Boris, Boutonnat, Jean, Ribuot, Christophe, Cracowski, Jean-Luc
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396598/
https://ncbi.nlm.nih.gov/pubmed/22808263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040792
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