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Chemical and genetic evidence for the involvement of Wnt antagonist Dickkopf2 in regulation of glucose metabolism

Mutations in Wnt receptor LRP5/6 and polymorphism in Wnt-regulated transcription factor TCF7L2 are associated with dysregulation of glucose metabolism. However, it is not clear whether Wnt antagonist Dickkopf (Dkk) has a significant role in the regulation of glucose metabolism. Here, we identified s...

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Detalhes bibliográficos
Main Authors: Li, Xiaofeng, Shan, Jufang, Chang, Woochul, Kim, Ingyu, Bao, Ju, Lee, Ho-Jin, Zhang, Xinxin, Samuel, Varman T., Shulman, Gerald I., Liu, Dakai, Zheng, Jie J., Wu, Dianqing
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396493/
https://ncbi.nlm.nih.gov/pubmed/22733757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205015109
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