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The Wnt antagonist Dickkopf-1 promotes pathological type 2 cell-mediated inflammation

Exposure to a plethora of environmental challenges commonly triggers pathological type 2 cell-mediated inflammation. Here we report the pathological role of the Wnt antagonist Dickkopf-1 (Dkk-1) upon allergen challenge or non-healing parasitic infection. The increased circulating amounts of Dkk-1 po...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Chae, Wook-Jin, Ehrlich, Allison K., Chan, Pamela Y., Teixeira, Alexandra M., Henegariu, Octavian, Hao, Liming, Shin, Jae Hun, Park, Jong-Hyun, Tang, Wai Ho, Kim, Sang-Taek, Maher, Stephen E., Goldsmith-Pestana, Karen, Shan, Peiying, Hwa, John, Lee, Patty J., Krause, Diane S., Rothlin, Carla V., McMahon-Pratt, Diane, Bothwell, Alfred L.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758884/
https://ncbi.nlm.nih.gov/pubmed/26872695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.01.008
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