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Derivation Conditions Determine X-Reactivation Status in Female Human Induced Pluripotent Stem Cells
Female human induced pluripotent stem cell (hiPSC) lines exhibit variability in X-inactivation status. The majority of hiPSC lines maintain one transcriptionally active X (Xa) and one inactive X (Xi) chromosome from donor cells. However, at low frequency, hiPSC lines with two Xas are produced, sugge...
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主要な著者: | , , , , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
2012
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396435/ https://ncbi.nlm.nih.gov/pubmed/22770243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.05.019 |
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