Comparative dynamic transcriptome analysis (cDTA) reveals mutual feedback between mRNA synthesis and degradation

To monitor eukaryotic mRNA metabolism, we developed comparative dynamic transcriptome analysis (cDTA). cDTA provides absolute rates of mRNA synthesis and decay in Saccharomyces cerevisiae (Sc) cells with the use of Schizosaccharomyces pombe (Sp) as an internal standard. cDTA uses nonperturbing metab...

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Detalhes bibliográficos
Main Authors: Sun, Mai, Schwalb, Björn, Schulz, Daniel, Pirkl, Nicole, Etzold, Stefanie, Larivière, Laurent, Maier, Kerstin C., Seizl, Martin, Tresch, Achim, Cramer, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396375/
https://ncbi.nlm.nih.gov/pubmed/22466169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.130161.111
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