Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast

To obtain rates of mRNA synthesis and decay in yeast, we established dynamic transcriptome analysis (DTA). DTA combines non-perturbing metabolic RNA labeling with dynamic kinetic modeling. DTA reveals that most mRNA synthesis rates are around several transcripts per cell and cell cycle, and most mRN...

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Главные авторы: Miller, Christian, Schwalb, Björn, Maier, Kerstin, Schulz, Daniel, Dümcke, Sebastian, Zacher, Benedikt, Mayer, Andreas, Sydow, Jasmin, Marcinowski, Lisa, Dölken, Lars, Martin, Dietmar E, Tresch, Achim, Cramer, Patrick
Формат: Artigo
Язык:Inglês
Опубликовано: European Molecular Biology Organization 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049410/
https://ncbi.nlm.nih.gov/pubmed/21206491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.112
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