Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast

To obtain rates of mRNA synthesis and decay in yeast, we established dynamic transcriptome analysis (DTA). DTA combines non-perturbing metabolic RNA labeling with dynamic kinetic modeling. DTA reveals that most mRNA synthesis rates are around several transcripts per cell and cell cycle, and most mRN...

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Bibliografische gegevens
Hoofdauteurs: Miller, Christian, Schwalb, Björn, Maier, Kerstin, Schulz, Daniel, Dümcke, Sebastian, Zacher, Benedikt, Mayer, Andreas, Sydow, Jasmin, Marcinowski, Lisa, Dölken, Lars, Martin, Dietmar E, Tresch, Achim, Cramer, Patrick
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: European Molecular Biology Organization 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049410/
https://ncbi.nlm.nih.gov/pubmed/21206491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.112
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