Comparative dynamic transcriptome analysis (cDTA) reveals mutual feedback between mRNA synthesis and degradation

To monitor eukaryotic mRNA metabolism, we developed comparative dynamic transcriptome analysis (cDTA). cDTA provides absolute rates of mRNA synthesis and decay in Saccharomyces cerevisiae (Sc) cells with the use of Schizosaccharomyces pombe (Sp) as an internal standard. cDTA uses nonperturbing metab...

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Autors principals: Sun, Mai, Schwalb, Björn, Schulz, Daniel, Pirkl, Nicole, Etzold, Stefanie, Larivière, Laurent, Maier, Kerstin C., Seizl, Martin, Tresch, Achim, Cramer, Patrick
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2012
Matèries:
Method
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396375/
https://ncbi.nlm.nih.gov/pubmed/22466169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.130161.111
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