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Evaluation of Sulfatase-Directed Quinone Methide Traps for Proteomics
Sulfatases hydrolytically cleave sulfate esters through a unique catalytic aldehyde, which is introduced by a posttranslational oxidation. To profile active sulfatases in health and disease, activity-based proteomic tools are needed. Herein, quinone methide (QM) traps directed against sulfatases are...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396293/ https://ncbi.nlm.nih.gov/pubmed/21570853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.04.044 |
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