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Inhibition of soluble epoxide hydrolase limits niacin-induced vasodilation in mice
BACKGROUND: The use of niacin in the treatment of dyslipidemias is limited by the common side effect of cutaneous vasodilation, commonly termed flushing. Flushing is thought to be due to release of the vasodilatory prostanoids PGD(2) and PGE(2) from arachidonic acid metabolism through the cyclooxyge...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396292/ https://ncbi.nlm.nih.gov/pubmed/22526297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e3182580a5d |
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