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Genetic Polymorphisms of CYP2C8 in the Czech Republic

Aim: CYP2C8 represents 7% of the hepatic cytochrome system and metabolizes around 5% of drugs in phase I processes. It also plays a significant role in metabolism of endogenous compounds. More than 20 single-nucleotide polymorphisms (SNPs) have been noted, mainly in exons 3, 5, and 8. The most studi...

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Bibliografske podrobnosti
Main Authors: Pechandova, Kristina, Buzkova, Helena, Matouskova, Olga, Perlik, Frantisek, Slanar, Ondrej
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396005/
https://ncbi.nlm.nih.gov/pubmed/22313047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/gtmb.2011.0275
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