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Genetic Polymorphisms of CYP2C8 in the Czech Republic
Aim: CYP2C8 represents 7% of the hepatic cytochrome system and metabolizes around 5% of drugs in phase I processes. It also plays a significant role in metabolism of endogenous compounds. More than 20 single-nucleotide polymorphisms (SNPs) have been noted, mainly in exons 3, 5, and 8. The most studi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396005/ https://ncbi.nlm.nih.gov/pubmed/22313047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/gtmb.2011.0275 |
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