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Lipid-lowering effect of fluvastatin in relation to cytochrome P450 2C9 variant alleles frequently distributed in the Czech population

BACKGROUND: CYP2C9*3 allele has been reported to correlate with increased plasma concentration of fluvastatin active form in healthy volunteers. We analyzed the correlation between the CYP2C9 genotype and cholesterol-lowering effect of fluvastatin in human hypercholesterolemic patients. MATERIAL/MET...

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Detalhes bibliográficos
Main Authors: Buzková, Helena, Pechandová, Kristina, Danzig, Vilém, Vařeka, Tomáš, Perlík, František, Žák, Aleš, Slanař, Ondřej
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560696/
https://ncbi.nlm.nih.gov/pubmed/22847201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.883272
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