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In silico labeling reveals the time-dependent label half-life and transit-time in dynamical systems

BACKGROUND: Mathematical models of dynamical systems facilitate the computation of characteristic properties that are not accessible experimentally. In cell biology, two main properties of interest are (1) the time-period a protein is accessible to other molecules in a certain state - its half-life...

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Autors principals: Maiwald, Thomas, Blumberg, Julie, Raue, Andreas, Hengl, Stefan, Schilling, Marcel, Sy, Sherwin KB, Becker, Verena, Klingmüller, Ursula, Timmer, Jens
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395849/
https://ncbi.nlm.nih.gov/pubmed/22369292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-13
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