Mechanisms of GnRH-Induced Extracellular Signal-Regulated Kinase Nuclear Localization

Gonadotropin-releasing hormone receptors (GnRHR) mediate activation and nuclear translocation of the extracellular signal regulated kinases 1 and 2 (ERK) by phosphorylation on the TEY motif. This is necessary for GnRH to initiate transcriptional programmes controlling fertility, but mechanisms that...

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Main Authors: Caunt, Christopher J., Perett, Rebecca M., Fowkes, Robert C., McArdle, Craig A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395631/
https://ncbi.nlm.nih.gov/pubmed/22808094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040077
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