Ubiquitin C-Terminal Hydrolase L1 in Tumorigenesis

Ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1, aka PGP9.5) is an abundant, neuronal deubiquitinating enzyme that has also been suggested to possess E3 ubiquitin-protein ligase activity and/or stabilize ubiquitin monomers in vivo. Recent evidence implicates dysregulation of UCH-L1 in the pathogene...

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Autores principales: Hurst-Kennedy, Jennifer, Chin, Lih-Shen, Li, Lian
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395355/
https://ncbi.nlm.nih.gov/pubmed/22811913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/123706
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